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SKINDNA™

SkinDNA™ is a revolutionary DNA laboratory test that examines 16 genetic markers (SNPs) in 5 categories associated with skin aging:

Category 1
Firmness + Elasticity

Category 2
Wrinkling (A.G.E.)

Category 3
Sun Damage + Pigmentation

Category 4
Free Radical Damage

Category 5
Sensitivty + Inflammation


After mailing your saliva sample for testing, your DNA results are used to scientifically create a personalised guide that allows you to advance beyond the 'one-size-fits-all' suggestions - using the right skincare ingredients targeted to your own genetic blueprint.

SkinDNA™ allows you to take the guesswork out of skin care, instead using science to identify a personalized strategy. Discover with a simple cheek swab (featured above)



WHY? We know that not every skincare product is going to suit everyone no matter how much the cosmetic industry tells you. And this is why there are so many different brands out there and literally thousands of different products.

Let SkinDNA™ help YOU become more aware of the most suitable skincare ingredients to look for from your favourite brands - based on your DNA. . We can all live beautifully longer

What to do

HERE's
WHAT TO DO

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Results

Results

A glimpse into SkinDNA's™ Sample Report.
Up to seven pages all about your skin.
*Report layout may vary based on region

  Help


FAQ

Frequently Asked Questions
Answers to common questions about SkinDNA™

Read More


Need help with your results?

Option 1
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Option 2
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Challenge one of our team members and ask them ANYTHING about your results.
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Locations

Too far? Take your results to any beauty clinic and we'll help them help you.

(SkinDNA MD service + additional fee may apply, please check your nearest stockist)

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Contact Us

An entire organization devoted to helping you.
Our team is ready to help answer your questions and to help guide you on your journey to reaching your skin aging prevention goals.

Phone
Call now to speak to one of our SkinDNA representatives.

1300 795 295

Email
For General Questions, Sales, or Questions about Your Results please fill form below

Distribution, Partnering and Reselling
SkinDNA™ offers exclusive distribution, partnering and reselling opportunities. For companies interested in excelling in the area of skin prevention by providing a unique genetic testing service to their customers or patients.

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Locations
  • Australia - SkinDNA™
    New South Wales
    BeautyLogic
    Medispa and Cosmetic Clinic
    Visit Website

    196 The Boulevarde
    Fairfield Heights NSW
    1300 196 196
    Refine
    Cosmetic Clinic
    Visit Website

    Suite 1504 101 Grafton Street
    Bondi Junction NSW
    1300 788 742
    Rejuven8 Clinic
    Penrith
    Visit Website

    Suite 1 / 344 High St
    Penrith NSW
    02 4732 4009
    Victoria
    Dr Vivienne Finnegan
    Vitality Plus

    Cheltenham
    3192
    03 9584 7304
    Queensland
    Vivente Skincare
    Caring more for skin
    Visit Website

    Grange, Brisbane
    07 3356 5959
  • Canada - SkinDNA™
    Vital Beauty Products Inc.
    Distributor
    Visit Website

    Distributor Nationwide
    Contact for information
    416 323 7788
    Body and Soul
    Med + Day Spa
    Visit Website

    214 Queen Street
    South Streetsville ON
    905 814 0659
    Mellennia Clinic
    Day Spa & Laser
    Visit Website

    74 Queen Street
    West Brampton ON
    905 453 6214
  • United Kingdom - SkinDNA™
    Beautopia
    Mobile Spa
    Visit Website

    13 Charles Harrods Court
    Harrods Village UK
    020 8741 5888
    The Borland Studio
    For Health & Beauty
    Visit Website

    No.19 Woodside Place
    Glasgow Charing X Strathclyde
    141 353 1069
  • USA - SKINSHIFT®
    SKINSHIFT®
    By Ruthie Harper MD
    Visit Website

    Stockist and Distributor
    Nationwide
    1-855-DNA-SKIN
  • Hong Kong + Greater China VITA-Genes™
    Vita-Genes
    Partner
    Visit Website

    Nationwide
    Contact for more information.
    +852 2393 2343
  • Brazil - DNAage™
    Visiongen
    Distributor
    Visit Website

    Nationwide
    Contact for more information.
  • Japan - GSdnaskin™
    GSdnaskin
    Distributor
    Visit Website

    Distributor Nationwide
    Visit website for information
  • Europe - SkinDNA™
    Netherlands
    Nydia Styling & Beauty
    Stockist
    Visit Website

    Contact +316 121 35748
    Azorenweg 42
    1339 VN Almere Buiten
    Denmark
    The Beauty Academy
    Stockist
    Visit Website

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Our Company

SkinDNA™ is a Wellbeing Genomics company founded by leading researchers and specialists in genetic analysis and skin therapies. The company is dedicated to the research and development of new therapies for skin improvement tailored to an individuals genetic makeup.

Genetic Variations and Personalized Health... One size does not fit all.


Our Products
It's a fact of life that our genes play a large role in determining who we are, also who we will become. The evidence of this isn't limited to the realm of science, it's expressed in our everyday sayings like "You have your mothers eyes", "Your great uncles nose", but even in the everyday, the biological outcomes of our organs is determined in large part by our genes, and since the skin is the body's largest and one of the most critical organs, we set out to determine which genes play a role in this determination.

This set forth the world's first and largest Dermagenetics database, our most significant achievement to date, with access to more than 10,000 DNA population wide samples from various ethnic groups.

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BUY

SkinDNA Kit Includes:
Our easy-to-use DNA Collector
Postage paid return package
Detailed Instructions
Report Highlights:
7 page SkinDNA™ Report
Topical Ingredient Matches
Nutritional Supplement Matches
Professional Treatment Matches
Personal Consultation
On-going clinic support
Locations
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Copyright © 2013 SkinDNA Genetic Test. All Rights Reserved.
Also visit SkinDNA Clinics

1. Firmness + Elasticity 2. Wrinkling (A.G.E.) 3. Sun Damage + Pigmentation 4. Free Radical Damage 5. Sensitivity + Inflammation

Category 1

Firmness + Elasticity

COLLAGEN IS AN IMPORTANT ELEMENT OF HUMAN SKIN, IN FACT IT IS THE PRINCIPLE STRUCTURAL PROTEIN HOLDING THE SKIN TOGETHER.

The genes in this category are involved in slowing the breakdown and degradation of Collagen Fibers found in the extracellular matrix of human tissue. Key variations tested in this category can identify if the synthesis and degradation process of Collagen is in balance, or if the degradation predominates (increased MMP levels) that can result in the appearance of premature wrinkling, loss of youthful looks and other ageing skin traits.


DID YOU KNOW

1 in 3 people have a genetic variation that predisposes their skin to accelerated wrinkling.


It is well established that Collagen is an important element of human skin1; in fact it is the principle structural Protein holding the skin together. Representing 75% of the skin's dry weight2 it keeps the skin firm, plump and wrinkle-free. The quantity and quality of the Collagen plays a major role in the skin's appearance. Like many components of the body, Collagen undergoes continuous turnover: new Collagen is continually produced and recycled throughout life.

At a younger age, the synthesis of Collagen predominates, whereas after about the age of 40, the degradation of Collagen picks up speed .4 This degradation process is precipitated by a protein called Matrix Metallopeptidase-1 (MMP's) or Collagenase. As we age our bodies struggle to replenish stores of collagen, and some people are genetically primed to break down collagen faster than others.


In healthy, youthful skin, the synthesis and degradation of Collagen is in balance: damaged or redundant Collagen is degraded while the deficit is replenished by the ongoing synthesis4. Unfortunately, this intricate balance gets disrupted when there is an oversupply of MMP1: too little of the matrix is synthesized and too much is degraded .1,3 The more this occurs the more winkles, roughness and sagginess one tends to have. MMP levels are known to increase with age as a result of photo aging5 as well as natural aging .3,4

Gene Table

SkinDNA™ Gene Descriptor Genotype Description
s700298/

Collagen Stimulation

1G1G Involved in slowing the breakdown and degradation of Collagen fibers found in the extracellular matrix of human tissue.

Chromosome Location: 11q21-q22

s706371/

Glutathione Production

TT Normalises skin cell functions disrupted by oxidative stress including MMP-1 production

Chromosome Location: 3q21.3

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1. Firmness + Elasticity 2. Wrinkling (A.G.E.) 3. Sun Damage + Pigmentation 4. Free Radical Damage 5. Sensitivity + Inflammation

Category 1
Firmness + Elasticity

Collagen is an important element of human skin, in fact it is the principle structural protein holding the skin together.

The genes in this category are involved in slowing the breakdown and degradation of Collagen Fibers found in the extracellular matrix of human tissue. Key variations tested in this category can identify if the synthesis and degradation process of Collagen is in balance, or if the degradation predominates (increased MMP levels) that can result in the appearance of premature wrinkling, loss of youthful looks and other ageing skin traits.


DID YOU KNOW

1 in 3 people have a genetic variation that predisposes their skin to accelerated wrinkling.

More
More Cont.
Genes
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1. Firmness + Elasticity 2. Wrinkling (A.G.E.) 3. Sun Damage + Pigmentation 4. Free Radical Damage 5. Sensitivity + Inflammation

Category 2
Wrinkling (A.G.E.)

If you're like most people, then no one has ever told you about glycation. Affecting Collagen and Elastin fibers, glycation is now well recognised to be a leading cause of accelerated skin aging.

The genes in this category play a key role in skin Glycation. They are responsible for controlling serum glucose levels, energy intake and energy release. Having variations in these genes can alter the functioning of normal glucose levels and energy metabolism. While glucose is a vital cellular fuel, if not completely metabolised by the body Glycation can occur, leading way to wrinkling, dryness and laxity.


DID YOU KNOW

1 in 2 people are predisposed to reduced genetic protection against Glycation.

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More Cont.
Genes
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1. Firmness + Elasticity 2. Wrinkling (A.G.E.) 3. Sun Damage + Pigmentation 4. Free Radical Damage 5. Sensitivity + Inflammation

Category 3
Sun Damage + Pigmentation

The sun's UV rays are one of the most significant causes of premature skin aging. your genes play a crucial role in determining how well your skin can naturally cope under the strains of the sun.

The genes in this category can reveal if your skin has a greater or lesser natural genetic solar protection factor (gSPF™), and based on your results can provide you with a unique, enhanced skin care protection strategy that is specially designed to provide the utmost sun protection for your skin based on your genes. And we dont mean sunscreen!


DID YOU KNOW

2 in 5 people have a genetic variation that affects their skin's UV defences.

More
More Cont.
Genes
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1. Firmness + Elasticity 2. Wrinkling (A.G.E.) 3. Sun Damage + Pigmentation 4. Free Radical Damage 5. Sensitivity + Inflammation

Category 4
Free Radical Damage

Similar to rust appearing on the metal of a car, the oxidation phenomenon causes significant damage and impairment to skin cells.

Research at SkinDNA™ has shown that the amount of antioxidants in your bidy is directly proportional to a healthy long term appearance of your skin!

A number of skin related genetic polymorphisms have been found to alter the production of these molecules. Your SkinDNA Free Radical Damage score is the single most powerful indication of your body's genetic Antioxidant abilities.


DID YOU KNOW

1 in 2 people are genetically predisposed to reduced skin Antioxidant protection.

More
More Cont.
Genes
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1. Firmness + Elasticity 2. Wrinkling (A.G.E.) 3. Sun Damage + Pigmentation 4. Free Radical Damage 5. Sensitivity + Inflammation

Category 5
Sensitivity + Inflammation

The regulation of inflammation is largely regulated by your genes. Excessive inflammation is one of the most common themes in early onset aging.

The genes that make up your Inflammation + Sensitivity score play a key role in signalling the release of inflammatory proteins and help in the detoxifying of Environmental Pollutants and Xenobiotics.


DID YOU KNOW

8 in 10 people have a genetic variation that can cause an over reactive inflammation response.

More
Genes
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Collagen

Collagen is the principle structural protein that holds the skin together.

Collagen is just one of thousands of different proteins in the body. The most abundant protein is collagen. In fact, collagen makes up more than one third of all protein in the body and about 75% of the skin.

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Protein

Protein are the building blocks of life. They are essential in helping to build the human body including muscle, bone, blood and collagen.

Protein enables the body to function properly. They are used in all sorts of ways: to transport nutrients and oxygen to vital organs including the skin, and are essential tools needed for cellular repair.

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MMP's

Matrix Metalloproteinases (MMP) are critical players in the skin's physiology.

They break down damaged or worn out structural proteins, facilitate the second phase of wound healing, clear pathways for movement of immune cells to infected areas, and so forth.

MMP's are also involved in the breakdown and degradation of the collagen fibrils found in the extracellular matrix of human tissue

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Collagen

Collagen is the principle structural protein that holds the skin together.

Collagen is just one of thousands of different proteins in the body. The most abundant protein is collagen. In fact, collagen makes up more than one third of all protein in the body and about 75% of the skin.

Back
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Elastin

Elastin is a protein found in connective tissue that is elastic.
In the skin, Elastin helps keep flexibility by providing a bounce-back reaction if skin is pulled or pinched.


Enough elastin in the skin means that the skin will return to its normal shape after a pull or a pinch. It also helps keep skin smooth as it stretches to accommodate normal activities like flexing a muscle or opening and closing the mouth to talk or eat.

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Glucose

Glucose is the body's prime source of fuel for generating energy.
It is a type of sugar that comes from digesting carbohydrates into a chemical that we can easily convert to energy.


But glucose has its dark side. If not properly metabolised Glucose can bind tightly to proteins and form abnormal chemical bridges that progressively damage tissue elasticity. This process is referred to as Glycation.

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Glycation

Glycation occurs when excess bodily glucose molecules link to the skin's Collagen and Elastin fibers.

This cross-linking can form chemical bridges between these proteins. Glycated fibers can become rigid, less elastic and have reduced regenerative ability, which can lead to damage such as laxity, cracking and thinning skin.

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Ultraviolet Light

UV light is a form of radiation that is found in sunlight.

Most people are aware of the effects of overexposure to UV radiation through the painful condition of Erythema (Sunburn). There are 2 main forms of UV radiation that impact our skin, UVA rays and UVB rays.

UVA Rays: known as the 'aging' rays, they are a form of radiation that has very little immediate visible effects. The effects of UVA rays often do not become apparent until years down the track often after the damage has already been done. Its spectrum is strong enough to bypass the top layers of skin and damage the deeper layers know as the dermis. It is predominantly these rays that cause skin to prematurely age.

UVA rays mostly come through when the sun is at an angle generally between 8am - 10am and 2pm - 6pm. These rays become magnified when cloudy or overcast and when reflecting through glass such as when driving or near windows.

UVB Rays: Known as the 'burning' rays, they are a form of radiation that has a great deal of immediate visible effect. Unlike UVA rays its spectrum isn't strong enough to travel into the deeper layers of skin therefore most of the damage is done on the superficial layers taking the form of sunburns, pealing, swelling, pigmentation and browning of the skin.

UVB rays are most predominant when the sun is directly shining down between 10am -2pm.

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8-oxoG radicals

8-oxoG radical is considered to be one of the worst types of free radical species. This radical is generated by exposure to ionizing radiations such as UV light.

8-oxo-G radicals can cause harmful mutations within the DNA structure6 and can ultimately affect the functioning of crucial genes that play vital roles in collagen synthesis, protection and other central duties.

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Melanin

Pigment (color) found in the skin.

Melanin is essential in protecting the skin from the sun.


The release of melanin helps absorb and breakdown the sun's harmful UV rays and UV-generated free radicals.5 The reason some people are darker than others is because of the amount of melanin their body naturally produces.

The more efficient the body is at producing melanin the more your skin is able to withstand (to a degree) the suns UV rays. Pigmentation has been widely viewed as a photoprotectant and research has shown that darkly pigmented skin is at a lower risk of photocarcinogenesis than fair skin.

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Photoproducts

A form of DNA damage, they are chemical reactions that are produced by the action of light.

They are formed mainly from UV light omitted by the sun or by artificial means such as a Solarium. Photoproducts can account for one quarter of all DNA damage.

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Free Radicals

Free radicals are highly reactive short lived molecules that can damage virtually any molecule in our body - including the important cellular structures found in the body's largest organ - the skin.

This kind of free radical damage leads to the generation of even more free radicals. It's a chain reaction that can wreck havoc in every layer of the skin - including the Hypodermis, Dermis and the particularly vulnerable epidermis!

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Glutathione

Glutathione is one of the body's most important intracellular antioxidants.

Glutathione is one of the body's most important intracellular antioxidants.

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Hydrogen Peroxide

Hydrogen peroxide is produced as a by-product of Superoxide radicals during the oxygen metabolising process.

As oxygen enters the body Superoxides Dismutase (SOD) convert Superoxides found in oxygen into hydrogen peroxide.
Hydrogen peroxide is then converted into water and is excreted by your body.

This constant cycle is a necessary process in order for our body to function. However, if hydrogen peroxide is not completely broken down Hydroxyl radicals may be formed.

Hydroxyl radicals are a type free radical that can be very harmful to your body. They can cause cellular damage, DNA Mutations and can influence aging and longevity.

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Oxidation

Oxidation occurs when the generation of free radicals within our body exceeds the body's ability to neutralize and eliminate them.

This imbalance can result from a lack of antioxidant capacity caused by diminished production, or by an over-abundance of free radical production. If not broken down properly, the excess free radicals can damage a cell's lipids, protein and DNA structure, inhibiting normal function.

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Quniones

Quinones are highly active molecules that can stem from Environmental pollutants including UV radiation, industrial plants, exhaust fumes, carbon and cigarette smoke.

Once absorbed into the skin, if they are not efficiently broken down can begin to oxidize within the skin's wall.

This can cause skin to become photosensitive, accelerate collagen breakdown and heighten the skin's sensitivity to Environmental pollutants.

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Superoxide Dismutase (SOD)

Superoxide Dismutase (SOD) is arguably the body's most crucial antioxidant.

It plays a critical role in reducing oxidative stress and is responsible for breaking down the most dangerous free radical of all: Superoxide radicals.

Superoxide radials are produced as a by-product of Oxygen. SOD is essential in converting superoxide radicals into a less harmful substance called Hydrogen Peroxide. From there Hydrogen Peroxide is then broken down into water and is safely excreted from the body.

If Superoxide radicals are not broken down, they can cause tremendous damage to your body including inflammatory problems, premature aging and can affect longevity.

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Xenobiotics

Harmful toxins that are found in pollutants such as PAHs. These harmful toxins surround us in our day to day living.

If not broken down epoxides can be extremely harmful to the body releasing a wave of free radical mayhem.

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Polycyclic Aromatic Hydrocarbons (PAH's).

span style="color: #ff6600; font-weight: bold;">Highly toxic chemical compounds.

Released from everyday pollutants such as the burning of wood, coal, diesel, and waste, industrial activities, exhaust fumes and cigarette smoke.

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Epoxides

Chemical compounds which cause trauma and damage to skin cells.

They can set the foundation for free radical havoc, increase cellular damage, cause collagen to breakdown and enhance skin sensitivity.

These chemical compounds can stem from air pollution, cigarette smoke and exhaust fumes.

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 FAQ